Phépton MGF

Força                                         : 2mg/frasco

Apresentação                                : Cada caixa contém 10 frascos de 2mg cada

Dosagem recomendada           : 200-300mcg/dia

Mechano growth factor is a novel splice variant of the Insulin-Like Growth Factor-1. It is actually originally called MGF because the RNA form of it is expressed in muscle tissues in response to the overload or/and damage of muscle growth tissue. The C-terminal peptide of the MGF is a crucial region for the alternative splicing of the peptide. The alternative splicing in the MGF is brought about by the shift in the reading frame in which a specific C-terminal sequence (E-domain) is encoded by exon 5 and the first part of the exon 6. Another interesting point in MGF is that, because of the E domain it contains, MGF can act on muscles independently from the rest of the molecule. Furthermore, MGF can elicit very different effects with mGF promoting satellite cells proliferation and IGF-1 inducing differentiation activity of the IGF peptide.